Bastyr Center for Natural Health, Seattle, Washington
Health Information
Overview Health Conditions and Concerns Conditions A-M Conditions N-Z Healthy Lifestyle Tips Bastyr Health-E News News and Events Recommended Reading List Recipes National and Community Resources
Schedule an appointment today
Brain Health | Oral Bacteria in the Brain Might Contribute to Alzheimer’s
Woman smiling in her car

Preventing and managing gum disease might protect you from chronic inflammatory diseases like Alzheimer’s.

Oral Bacteria in the Brain Might Contribute to Alzheimer’s

Researchers studying the bacteria in the mouth have found that bacteria that causes gum disease may play a role in the course of Alzheimer’s disease, according to the Journal of Alzheimer’s Disease.

The hidden world of the digestive tract, beginning with the mouth, is populated by a vastly diverse group of microorganisms. Many of these microbes are critical for our good health, but in unhealthy conditions, disease-causing microbes may flourish and cause health problems in other parts of the body.

Bacteria in the brain

In the study, brain tissue samples from 10 deceased people diagnosed with Alzheimer’s disease were treated with antibodies (immune system proteins) that specifically target Porphyromonas gingivalis, one of the bacteria that commonly cause gum disease. In four out of the 10 cases, the antibodies accumulated on surfaces of specialized immune cells of the brain, suggesting that the bacterium P. gingivalis had been in the brain. The antibodies did not accumulate in any of the brain tissue samples from 10 deceased people without Alzheimer’s disease.

Gum disease may trigger chronic inflammation

"These results indicate that the brain of Alzheimer’s disease patients is at greater risk of secondary infection from the periodontal pathogen, P. gingivalis, which has long been implicated in chronic and severe adult periodontitis [gum disease],” the study’s authors said. They proposed that this type of brain infection could trigger chronic inflammation, which could speed the progression of memory loss and other Alzheimer’s disease symptoms.

Although these findings do not establish a clear link between gum disease and Alzheimer’s disease, it does add to the growing body of evidence that gum disease–causing bacteria may play a role in memory loss and dementia. Previous studies have found connections between gum disease and other chronic inflammatory conditions, such as diabetes and heart disease.

Keep your gums healthy

Preventing and managing gum disease will help you keep your teeth longer and might protect you from chronic inflammatory diseases like Alzheimer’s disease. Here are some ways to keep your gums healthy and strong:

  • Don’t smoke. If you do, try to quit. Smoking contributes to health problems all over the body, including in the mouth.
  • Brush, floss and visit the hygienist. Home dental hygiene twice daily helps keep your teeth and gums healthy, and deep cleaning by a dental hygienist once or twice a year helps keep plaque and tartar, which are generated by gum disease–causing bacteria, under control.
  • Fight with folate. A mouthwash with 0.1 percent folic acid has been found to reduce inflammation and bleeding in people with gum disease. However, tell your doctor if you are using this treatment, because exposure to this relatively large amount of folic acid, even though most of is spit out, might interfere with certain medications and laboratory tests.
  • Consider CoQ10. Coenzyme Q10, known for its importance in preventing and treating heart disease, has also been found to improve gum disease symptoms.

(J Alzheimers Dis 2013;36:665–77)

Maureen Williams, ND, completed her doctorate in naturopathic medicine at Bastyr University in Seattle and has been in private practice since 1995. With an abiding commitment to access to care, she has worked in free clinics in the U.S. and Canada, and in rural clinics in Guatemala and Honduras where she has studied traditional herbal medicine. She currently lives and practices in Victoria, B.C., and lectures and writes extensively for both professional and community audiences on topics including family nutrition, menopause, anxiety and depression, heart disease, cancer and easing stress. Dr. Williams is a regular contributor to Healthnotes Newswire.

Learn More About It

1 | 2 | 3 | 4 | 5 | 6 | 7 |

Find a Provider

Want to find the provider that's right for you? Learn more about our health care providers.  »

Bastyr Center Disclaimer

The health information contained in this site is not intended as medical advice and should not be considered a substitute for appropriate medical care. Any products mentioned in studies cited in Healthnotes articles are not necessarily endorsed by Bastyr. As with any product, consult with a natural health practitioner to discuss what may be best for you.


Appointments: 206.834.4100
Bastyr Center clinic appointments

Submit a contact request or call us to schedule an appointment »

Bastyr University Clinic in San Diego

Are you looking for Bastyr University Clinic, our new teaching clinic in San Diego? More »

Learn More About Our Services

Natural medicine can treat many types of conditions including:

More treatable health conditions »

Bastyr Center healthcare providers

Interested in finding a provider who's right for you? We recommend that your first visit at BCNH be with a Naturopathic Medicine Provider. »

Home  | Health Information  | Health Care Services  | Our Providers  | Patient Care  | Dispensaries

About BCNH  | Contact Us  | Appointments  | Privacy Policy  | Site Map | Bastyr University